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Th17: An Effector CD4 T Cell Lineage with Regulatory T Cell Ties

✍ Scribed by Casey T. Weaver; Laurie E. Harrington; Paul R. Mangan; Maya Gavrieli; Kenneth M. Murphy

Book ID
116570627
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
260 KB
Volume
24
Category
Article
ISSN
1074-7613

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Expanding the effector CD4 T-cell repert
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✍ Laurie E Harrington; Paul R Mangan; Casey T Weaver πŸ“‚ Article πŸ“… 2006 πŸ› Elsevier Science 🌐 English βš– 259 KB

The Th1/Th2 paradigm has provided the framework for understanding CD4 T-cell biology and the interplay between innate and adaptive immunity for almost two decades. Recent studies have defined a previously unknown arm of the CD4 T-cell effector response -the Th17 lineage -that promises to change our