The role of IL-12 in the maintenance of
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Cris S. Constantinescu; Brian D. Hondowicz; M. Merle Elloso; Maria Wysocka; Gior
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Article
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1998
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John Wiley and Sons
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English
⚖ 116 KB
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IL-12 initiates the development of cell-mediated immunity by promoting the differentiation of naive T cells into the Th1 phenotype, and is essential in the development of a Th1 immune response to the intracellular protozoan parasite, Leishmania major. The present study investigated whether IL-12 is