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TGFβ-inducible early gene-1 (TIEG1) mutations in hypertrophic cardiomyopathy

✍ Scribed by J. Martijn Bos; Malayannan Subramaniam; John R. Hawse; Imke Christiaans; Nalini M. Rajamannan; Joseph J. Maleszewski; William D. Edwards; Arthur A.M. Wilde; Thomas C. Spelsberg; Michael J. Ackerman


Book ID
112120126
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
399 KB
Volume
113
Category
Article
ISSN
0730-2312

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TGFβ inducible early gene-1 (TIEG1) and
✍ Nalini M. Rajamannan; Malayannan Subramaniam; Theodore P. Abraham; Vlad C. Vasil 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 539 KB

## Abstract Cellular mechanisms causing cardiac hypertrophy are currently under intense investigation. We report a novel finding in the TGFβ inducible early gene (TIEG) null mouse implicating TIEG1 in cardiac hypertrophy. The TIEG^−/−^ knock‐out mouse was studied. Male mice age 4–16 months were cha