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TGFBR1 Signaling and Breast Cancer

✍ Scribed by Lakisha Moore-Smith; Boris Pasche

Publisher
Springer US
Year
2011
Tongue
English
Weight
172 KB
Volume
16
Category
Article
ISSN
1083-3021

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## Abstract The adipocyte‐derived peptide leptin acts through binding to specific membrane receptors, of which six isoforms (obRa‐f) have been identified up to now. Binding of leptin to its receptor induces activation of different signaling pathways, including the JAK/STAT, MAPK, IRS1, and SOCS3 si