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TGF-β2 induces transdifferentiation and fibrosis in human lens epithelial cells via regulating gremlin and CTGF

✍ Scribed by Ma, Bo; Kang, Qianyan; Qin, Li; Cui, Lijun; Pei, Cheng


Book ID
121737376
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
639 KB
Volume
447
Category
Article
ISSN
0006-291X

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## Abstract Retinal pigment epithelium (RPE) and transforming growth factor‐β (TGF‐β) have been shown to be involved in various retinal diseases. We have studied the role of inflammatory cytokines on the expression and secretion of TGF‐β in human RPE cells (HRPE). Confluent cultures of HRPE derived