TGF-β1 signalling in scars
✍ Scribed by K. Rolfe; J. Richardson; C. Vigor; A.O. Grobbelaar; C. Linge
- Book ID
- 119200838
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 42 KB
- Volume
- 59
- Category
- Article
- ISSN
- 1878-0539
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Transforming growth factor-β (TGFβ) signalling provides animal cells with a versatile means of driving developmental programmes and controlling cell behaviour, a role that is evident in the many effects of TGFβ-related cytokines on cell proliferation, differentiation, morphogenesis, tissue homeostas
## Abstract Transforming growth factor‐β1 (TGF‐β1) action is known to be initiated by its binding to multiple cell surface receptors containing serine/threonine kinase domains that act to stimulate a cascade of signaling events in a variety of cell types. We have previously shown that TGF‐β1 and BM