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TGF-β1 selectively suppresses PDGF receptor signaling pathways in MG-63 human osteosarcoma cell

✍ Scribed by Li-Man Hung; Chon-Haw Tsai; Jan-Kan Chen


Book ID
117175142
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
640 KB
Volume
61
Category
Article
ISSN
0024-3205

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Differential inhibitory effects of TGF-β
✍ Hiroyuki Mioh; Jan-Kan Chen 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 English ⚖ 980 KB

The growth of MG63 human osteosarcoma cell line in 5 % serum is stimulated by epidermal growth factor (EGF), platelet-derived growth factor (PDGF), or heparinbinding growth factor-1 (HBGF-1). The mitogenic effect of EGF and PDGF is completely blocked by TFG-f3 at 1 ng per ml and the effect of HBGF-1