The maturation of connective tissue involves the organization of collagen fibres by resident fibroblasts. Fibroblast attachment to collagen has been demonstrated to involve cell surface receptors, integrins of the beta 1 family. Integrins are associated with cytoplasmic actin of microfilaments eithe
✦ LIBER ✦
TGF-β1 and integrin synergistically facilitate the differentiation of rat podocytes by increasing α-smooth muscle actin expression
✍ Scribed by Chien-An Chen; Jyh-Chang Hwang; Jinn-Yuh Guh; Jer-Chia Tsai; Hung-Chun Chen
- Book ID
- 119383088
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 233 KB
- Volume
- 148
- Category
- Article
- ISSN
- 1931-5244
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We have reported that Cellular Retinol Binding Protein-1 (CRBP-1) is expressed de novo during skin wound healing by a proportion of fibroblastic cells which then differentiate into myofibroblasts and express alpha-smooth muscle actin. In fibroblasts cultured from different tissues we have shown that