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TGF-β Suppresses EGF-Induced MAPK Signaling and Proliferation in Asthmatic Epithelial Cells

✍ Scribed by Semlali, Abdelhabib; Jacques, Eric; Plante, Sophie; Biardel, Sabrina; Milot, Julie; Laviolette, Michel; Boulet, Louis-Philippe; Chakir, Jamila

Book ID
120449265
Publisher
American Thoracic Society
Year
2008
Tongue
English
Weight
557 KB
Volume
38
Category
Article
ISSN
1044-1549

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## Abstract Polarized gastrointestinal epithelial cells form tight junctions that spatially separate apical and basolateral cell membrane domains. These domains harbor functionally distinct proteins that contribute to cellular homeostasis and morphogenesis. Transforming growth factor β (TGFβ) is a