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TGF-β inhibits Akt-induced transformation in intestinal epithelial cells

✍ Scribed by Yanna Cao; Chunyan Deng; Courtney M. Townsend Jr; Tien C. Ko

Book ID
113920413
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
501 KB
Volume
140
Category
Article
ISSN
0039-6060

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## Abstract Polarized gastrointestinal epithelial cells form tight junctions that spatially separate apical and basolateral cell membrane domains. These domains harbor functionally distinct proteins that contribute to cellular homeostasis and morphogenesis. Transforming growth factor β (TGFβ) is a