TGF-β induces apoptosis through Smad-mediated expression of DAP-kinase
✍ Scribed by Jang, Chuan-Wei; Chen, Chun-Hau; Chen, Chun-Chieh; Chen, Jia-yun; Su, Yi-Hsien; Chen, Ruey-Hwa
- Book ID
- 109912567
- Publisher
- Nature Publishing Group
- Year
- 2001
- Tongue
- English
- Weight
- 402 KB
- Volume
- 4
- Category
- Article
- ISSN
- 1465-7392
- DOI
- 10.1038/ncb731
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## Abstract Transforming growth factor‐β (TGF‐β) signaling is known to depend on the formation of Smad2/3‐Smad4 transcription regulatory complexes. However, the signaling functions of Smad2/3‐Smad4 during TGF‐β‐induced responses are obscure as TGF‐β also initiates a number of other signaling pathwa