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TGF-β as a therapeutic target in high grade gliomas – Promises and challenges

✍ Scribed by Joseph, Justin V.; Balasubramaniyan, Veerakumar; Walenkamp, Annemiek; Kruyt, Frank A.E.


Book ID
118179168
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
641 KB
Volume
85
Category
Article
ISSN
0006-2952

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## Abstract Multiple myeloma (MM) is an incurable hematological malignancy. Different studies demonstrated the occurrence of genetic and epigenetic alterations in MM. The aberrant methylation is one of the most frequent epigenetic alterations in human genome. This study evaluated the aberrant methy