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TGF-β and CD23 are involved in nitric oxide production by pulmonary macrophages activated by β-glucan fromParacoccidioides brasiliensis

✍ Scribed by Luiz de Pádua Queiroz; Marden Estevão Mattos; Marcelo Fernandes da Silva; Célio Lopes Silva

Book ID: 106119910
Publisher: Springer-Verlag
Year: 2009
Tongue: English
Weight: 560 KB
Volume: 199
Category: Article
ISSN: 0300-8584
DOI: 10.1007/s00430-009-0138-1

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## Abstract Mushrooms are known for their immune‐modulating and anti‐tumour properties. The polysaccharide fraction, mainly β‐glucans, is responsible for the immune‐modulating effects. Fungal β‐glucans have been shown to activate leukocytes, which depend on structural characteristics of β‐glucans.