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tgDCC-E1A gene therapy appears to be effective in recurrent head and neck squamous cell cancer,

Book ID
120870343
Publisher
Adis International Limited (now part of Wolters Kluwer Health)
Year
2000
Weight
133 KB
Volume
&NA;
Category
Article
ISSN
1173-8324

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A multicenter phase II study of tgDCC-E1
A multicenter phase II study of tgDCC-E1A for the intratumoral treatment of patients with recurrent head and neck squamous cell carcinoma
✍ Doug Villaret; Bonnie Glisson; Daniel Kenady; Ehab Hanna; Mary Carey; Lyon Gleic πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 114 KB πŸ‘ 2 views

## Background: The anti-cancer gene, e1a, can be complexed to a lipid carrier, dc-cholesterol:dope, to form tgdcc-e1a, which can be injected directly into tumors. ## Methods: Twenty-four patients with recurrent, unresectable, head and neck cancer were treated with intratumoral injections of tgdcc