Tetrapeptide-amide analogues of enkephalin: The role of C-terminus in determining the character of opioid activity
✍ Scribed by A.Z. Rónai; J.I. Székely; I. Berzétei; E. Miglécz; S. Bajusz
- Book ID
- 118313565
- Publisher
- Elsevier Science
- Year
- 1979
- Tongue
- English
- Weight
- 552 KB
- Volume
- 91
- Category
- Article
- ISSN
- 0006-291X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Anoplin, an antimicrobial, helical decapeptide from wasp venom, looses its biological activities by mere deamidation of its __C__‐terminus. Secondary structure determination, by circular dichroism spectroscopy in amphipathic environments, and lytic activity in zwitterionic and anionic v
Several forrnylpeptides, analogs of the chemotactic agent HCO-Met-Leu-Phe-OMe, having the HCO-Xaa-Leu-A'Phe-OMe and HCO-Xaa-Leu-A'Phe-Phe-OMe structures (A' Phe = (Z)-2,3-didehydrophenylalanine), have been synthesized. The biological activity of these ligands has been determined on human neutrophils