𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Tetrandrine suppresses LPS-induced astrocyte activation via modulating IKKs-IκBα-NF-κB signaling pathway

✍ Scribed by Shu-Ting Lin; Ying Wang; Yang Xue; De-Chun Feng; Yan Xu; Ling-Yun Xu

Publisher
Springer
Year
2008
Tongue
English
Weight
313 KB
Volume
315
Category
Article
ISSN
0300-8177

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Jagged1 regulates the activation of astr
Jagged1 regulates the activation of astrocytes via modulation of NFκB and JAK/STAT/SOCS pathways
✍ Eleonora Morga; Laila Mouad-Amazzal; Paul Felten; Tony Heurtaux; Mike Moro; Ales 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 467 KB

## Abstract The Notch pathway is implicated in many aspects of the central nervous system (CNS) development and functions. Recently, we and others identified the Notch pathway to be involved in inflammatory events of the CNS. To understand the implication of this pathway on astrocytes, we have stud

Roxatidine suppresses inflammatory respo
Roxatidine suppresses inflammatory responses via inhibition of NF-κB and p38 MAPK activation in LPS-induced RAW 264.7 macrophages
✍ Eu-Jin Cho; Hyo-Jin An; Ji-Sun Shin; Hye-Eun Choi; Jane Ko; Young-Wuk Cho; Hyung 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 638 KB

Roxatidine is a novel, specific, competitive H 2 -receptor antagonist that is used to treat gastric and duodenal ulcers, and which is known to suppress the growth of several tumors by reducing vascular endothelial growth factor (VEGF) expression. Nevertheless, it remains unclear whether roxatidine h

KiSS1 suppresses TNFα-induced breast can
KiSS1 suppresses TNFα-induced breast cancer cell invasion via an inhibition of RhoA-Mediated NF-κB activation
✍ Sung-Gook Cho; Dali Li; Lewis J. Stafford; Jian Luo; Melissa Rodriguez-Villanuev 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 324 KB

## Abstract Tumor necrosis factor‐alpha (TNFα) induces cancer development and metastasis, which is prominently achieved by nuclear factor‐kappa B (NF‐κB) activation. TNFα‐induced NF‐κB activation enhances cellular mechanisms including proliferation, migration, and invasion. KiSS1, a key regulator o

Proteasome inhibitors impair RANKL-induc
Proteasome inhibitors impair RANKL-induced NF-κB activity in osteoclast-like cells via disruption of p62, TRAF6, CYLD, and IκBα signaling cascades
✍ Estabelle Ang; Nathan J. Pavlos; Sarah L. Rea; Ming Qi; Tracy Chai; John P. Wals 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 595 KB

## Abstract Proteasome inhibitors represent a promising therapy for the treatment of relapsed and/or refractory multiple myeloma, a disease that is concomitant with osteolysis and enhanced osteoclast formation. While blockade of the proteosome pathway has been recently shown to influence osteoclast

Cl-IB-MECA enhances TRAIL-induced apopto
Cl-IB-MECA enhances TRAIL-induced apoptosis via the modulation of NF-κB signalling pathway in thyroid cancer cells
✍ Silvana Morello; Rosalinda Sorrentino; Amalia Porta; Giovanni Forte; Ada Popolo; 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 347 KB

## Abstract Apoptosis is an endogenous process that can be a useful anti‐cancer tool. This study aimed to investigate the effect of Cl‐IB‐MECA, adenosine receptor A3 agonist, on TRAIL‐induced apoptosis of thyroid carcinoma cells. Cl‐IB‐MECA enhanced TRAIL‐mediated apoptosis in FRO but not in ARO ce

Simvastatin, 3-hydroxy-3-methylglutaryl
Simvastatin, 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, suppresses osteoclastogenesis induced by receptor activator of nuclear factor-κB ligand through modulation of NF-κB pathway
✍ Kwang Seok Ahn; Gautam Sethi; Madan M. Chaturvedi; Bharat B. Aggarwal 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 French ⚖ 631 KB

## Abstract Simvastatin, an inhibitor of 3‐hydroxy‐3‐methylglutaryl coenzyme A reductase, is a cholesterol‐lowering drug that may play a role in bone metabolism through a mechanism that is not fully understood. Recently, receptor activator of NF‐κB ligand (RANKL), a member of the TNF superfamily, h