𝔖 Bobbio Scriptorium
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Tetramic and tetronic acids as β-secretase inhibitors

✍ Scribed by Paul Edwards


Book ID
113568715
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
108 KB
Volume
12
Category
Article
ISSN
1359-6446

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Tryptoline, a core structure of ochrolifuanine E, which is a hit compound from virtual screening of the Thai herbal database against BACE1 was used as a scaffold for the design of BACE1 inhibitors. The tryptoline was linked with different side chains by 1,2,3-triazole ring readily synthesized by cat