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Tetrahydroaminoacridine improves the recency effect in Alzheimer's disease

โœ Scribed by M Riekkinen; H Soininen; P Riekkinen Sr; J Kuikka; M Laakso; E.-L Helkala; J Partanen; P Riekkinen Jr


Book ID
117492132
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
116 KB
Volume
83
Category
Article
ISSN
0306-4522

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Tetrahydroaminoacridine (THA), a centrally acting anticholinesterase, was used in a two-month, double-blind, placebo-controlled crossover trial to treat 10 patients meeting DSM-111-R criteria for dementia of the Alzheimer type. Eight patients continued to take THA for a further three months. Nausea

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In 12 ambulant patients with a clinical diagnosis of probable Alzheimer's disease, a 12-week, double-blind, placebo-controlled study with 100 mg/day tetrahydroaminoacridine (THA) and 10 g/day lecithin is reported. The aim of the study was to find whether treatment would result in an improvement of c