Tetracyclines inhibit nitrosothiol production by cytokine-stimulated osteoarthritic synovial cells

Inhibition of tumor necrosis factor α–in

Inhibition of tumor necrosis factor α–induced prostaglandin E2 production by the antiinflammatory cytokines interleukin-4, interleukin-10, and interleukin-13 in osteoarthritic synovial fibroblasts: Distinct targeting in the signaling pathways

✍ Nada Alaaeddine; John A. Di Battista; Jean-Pierre Pelletier; Kayghobad Kiansa; J 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 368 KB 👁 1 views

## Objective: To investigate the effects of the antiinflammatory cytokines interleukin-4 (il-4), il-10, and il-13 on tumor necrosis factor alpha (tnfalpha)-induced prostaglandin e2 (pge2) release in the cellular signaling cascade on human osteoarthritis (oa) synovial fibroblasts. ## Methods: Huma