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Tetracycline-Mediated Regulation of Gene Expression within the Human Cytomegalovirus Genome

✍ Scribed by Michael A. McVoy; Edward S. Mocarski

Book ID
112272586
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
221 KB
Volume
258
Category
Article
ISSN
0042-6822

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## Abstract The CD44 adhesion receptor is silenced in highly malignant neuroblastomas (NBs) with __MYCN__ amplification. Because its functional expression is associated with decreased tumorigenic properties, __CD44__ behaves as a tumor suppressor gene in NB and other cancers. Given that the precise