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Tetracaine-Membrane Interactions: Effects of Lipid Composition and Phase on Drug Partitioning, Location, and Ionization

✍ Scribed by Zhang, Jingzhong; Hadlock, Theresa; Gent, Alison; Strichartz, Gary R.

Book ID
119920998
Publisher
Biophysical Society
Year
2007
Tongue
English
Weight
194 KB
Volume
92
Category
Article
ISSN
0006-3495

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## Abstract Concanavalin A (Con A) binding and Con A‐mediated hemadsorption to LM cells were found to decrease significantly at both 5–7Β°C and 15–19Β°C. The higher of these critical temperatures responds to a change in state of the membrane lipids and can be increased or decreased in cells where the