Tetrabenazine for hyperglycemic-induced hemichorea–hemiballismus

✍ Scribed by Oraporn Sitburana; William G. Ondo

• Book ID: 102503823
• Publisher: John Wiley and Sons
• Year: 2006
• Tongue: English
• Weight: 86 KB
• Volume: 21
• Category: Article
• ISSN: 0885-3185
• DOI: 10.1002/mds.21100

✦ Synopsis

Abstract

We reported a 74‐year‐old woman with new‐onset diabetes mellitus who presented with the sudden onset of mild left hemiparesis and marked left hemichorea–hemiballismus. Brain CT scan and MRI showed T1W, T2W, and DWI lesions in the right putamen and caudate, which have been previously reported in cases of hyperglycemic‐induced hemichorea–hemiballismus (HIHH). The patient dramatically responded to tetrabenazine within a day. Subsequent dose reductions lead to a reemergence of symptoms. Tetrabenazine improves a variety of hyperkinetic movement disorders but, to our knowledge, its use has never been reported for HIHH. © 2006 Movement Disorder Society