Tetanic LTP in guinea pig CA1 is associated with an increase in the NMDA receptor-mediated component of EPSCs and in the rate of depression by MK-801

Augmentation of locomotor activity by ch

Augmentation of locomotor activity by chronic phencyclidine is associated with an increase in striatal NMDA receptor function and an upregulation of the NR1 receptor subunit

✍ Taleen Hanania; Gilbert R. Hillman; Kenneth M. Johnson 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 271 KB 👁 2 views

Phencyclidine (PCP) is a drug of abuse that produces schizophrenia-like symptoms in humans and increases locomotor activity and stereotypic behavior in rodents. PCP-induced alteration in rat locomotor activity is thought to be mediated by an inhibition of N-methyl-D-aspartate (NMDA) receptors in the