Tests of functional equivalence between pimozide pretreatment, extinction and free feeding

✍ Scribed by Paul Willner; Kanwaljeet Chawla; David Sampson; Sophocles Sophokleous; Richard Muscat

• Book ID: 104653548
• Publisher: Springer
• Year: 1988
• Tongue: English
• Weight: 475 KB
• Volume: 95
• Category: Article
• ISSN: 0033-3158
• DOI: 10.1007/bf00181960

✦ Synopsis

Both pimozide pretreatment and free feeding caused within-session and between-session decrements in variable interval operant performance; response decrements generated under pimozide were maintained on transfer to free feeding, and vice versa. On subsequently testing under extinction conditions (after food deprivation and drug flee) large initial increases in responding were seen in all groups, and subsequent response decrements in extinction were steeper than in either pimozide or free feeding conditions. The effects of pimozide pretreatment do not resemble those of extinction, but may in some circumstances be functionally equivalent to a decrease in drive level.