Testosterone-stimulated weanlings as an alternative to castrated male rats in the Hershberger anti-androgen assay

The peripubertal male rat assay as an al

The peripubertal male rat assay as an alternative to the Hershberger castrated male rat assay for the detection of anti-androgens, oestrogens and metabolic modulators

✍ J. Ashby; P. A. Lefevre 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 142 KB

A range of chemicals with various levels of activity as actual or potential endocrine disrupters have been evaluated for activity in the peripubertal male rat assay. The chemicals studied included anti-androgens (vinclozolin), cyproterone acetate, flutamide, 2, 2-bis(4-chlorophenyl)-1,1-dichloroethy