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Testosterone augments polyphenol-induced DNA damage response in prostate cancer cell line, LNCaP

✍ Scribed by Hisamitsu Ide; Jingsong Yu; Yan Lu; Toshiyuki China; Tomoka Kumamoto; Tatsuro Koseki; Satoru Muto; Shigeo Horie

Book ID: 108586940
Publisher: John Wiley and Sons
Year: 2010
Tongue: English
Weight: 338 KB
Volume: 102
Category: Article
ISSN: 1347-9032
DOI: 10.1111/j.1349-7006.2010.01791.x

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BACKGROUND. Prostate cancer is the second leading cause of cancer death in men. The most common treatment of prostate cancer is androgen ablation therapy which leads to regression of the tumor due to increased cell death. However, at later stages, the tumor becomes resistant to androgen ablation. Ce