Testing the safety of clinical-grade mature autologous myeloid DC in a phase I clinical immunotherapy trial of CML
โ Scribed by Litzow, Mr; Dietz, Ab; Bulur, Pa; Butler, Gw; Gastineau, Da; Hoering, A; Fink, Sr; Letendre, L; Padley, Dj; Paternoster, Sf
- Book ID
- 111674313
- Publisher
- Informa plc
- Year
- 2006
- Tongue
- English
- Weight
- 213 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1465-3249
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and then 18 million for the fifth and sixth injections. The humoral immune responses of the patients were assessed by enzyme-linked immunoadsorbent assay, radioimmunoassay, and radioimmunoprecipitation. ## RESULTS. Thirteen of the 20 patients completed the immunization protocol. Eight of these 13
Twenty-two patients received specific active immunotherapy (TAA vaccine once per month for 3 months), with the duration of follow-up, as of July 1984, ranging from 3 months to 36 months (median, 21 months). Of these, seven had Dukes Bz, seven had Dukes C, and eight had Dukes D lesions. All received