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Testing the Hardy-Weinberg Equilibrium in the HLA System

✍ Scribed by Shinto Eguchi and Masaaki Matsuura


Book ID
125776896
Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
982 KB
Volume
46
Category
Article
ISSN
0006-341X

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Testing for Hardy-Weinberg equilibrium (HWE) is used routinely as an important initial step for genotype data quality checking. Departure from HWE can be caused by many factors, such as genotyping errors, population stratification, and disease association, if we use affected individuals only. In a s