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Testing Drugs on Human Osteoarthritic Articular Cartilage

โœ Scribed by J. Chayen; Lucille Bitensky; S. Mehdizadeh; Jane Dunham; J. Older


Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
430 KB
Volume
12
Category
Article
ISSN
0263-6484

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Objective. Human osteoarthritis (OA) is characterized by a pathologic shift in articular cartilage homeostasis toward the progressive loss of extracellular matrix (ECM). The purpose of this study was to investigate the ability of rAAV-mediated SOX9 overexpression to restore major ECM components in h