Testicular Function in Poor-Risk Nonseminomatous Germ Cell Tumors Treated With Methotrexate, Paclitaxel, Ifosfamide, and Cisplatin Combination Chemotherapy
โ Scribed by Pectasides, D.; Pectasides, E.; Papaxoinis, G.; Skondra, M.; Gerostathou, M.; Karageorgopoulou, S.; Kamposioras, C.; Tountas, N.; Koumarianou, A.; Psyrri, A.; Macheras, A.; Economopoulos, T.
- Book ID
- 119924721
- Publisher
- American Society of Andrology
- Year
- 2009
- Tongue
- English
- Weight
- 278 KB
- Volume
- 30
- Category
- Article
- ISSN
- 1939-4640
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Twenty-seven patients with metastatic nonseminomatous germ cell tumors were treated with Cisplatin, vinblastine, bleomycin, and low-dose methotrexate (PVB + M) combinations. Patients were divided into good-risk and poor-risk groups. All seven patients (100%) with good-risk factors achieved complete
Forty-four patients with nonseminomatous germ cell tumors with "poor prognostic features" were entered on the VAB-5 regimen and 38 are evaluable. VAB-5 represents an intensified version of the VAB-4 protocol. Poor prognostic features were considered to be bulky metastases (>5 cm in diameter), palpab