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Testicular effects of acrylonitrile in mice

✍ Scribed by R. Tandon; D.K. Saxena; S.V. Chandra; P.K. Seth; S.P. Srivastava

Book ID
118270060
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
839 KB
Volume
42
Category
Article
ISSN
0378-4274

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Acrylonitrile interaction with testicula
Acrylonitrile interaction with testicular DNA in rats
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In the present study we report the in vivo interaction of acrylonitrile (VCN) with testicular tissue in rats. Covalent binding of radioactivity to testicular tissue DNA was examined for a period of 72 hr after a single oral dose (46.5 mg/kg) of [2,3-14C] VCN. Maximal covalent binding was observed at