Test of Platelet Factor 3 Activity Using a Piezoelectric Crystal Sensor

✍ Scribed by S. Shihui; N. Lihua; Y. Shouzhuo

• Book ID: 102615619
• Publisher: Elsevier Science
• Year: 1995
• Tongue: English
• Weight: 349 KB
• Volume: 51
• Category: Article
• ISSN: 0026-265X
• DOI: 10.1006/mchj.1995.1040

✦ Synopsis

A quartz crystal detector was used to monitor the viscosity change during the plasma coagulation process, and the activity of platelet Factor 3 was tested by measuring the plasma-clotting time. The results show that the plasma-clotting time decreases with the increase of platelet concentration under certain conditions, and the plasma coagulation process is also affected by the temperature and the value of (\mathrm{pH}). In the investigation of some anti-blood factor drugs in clinical medical inspection, this method has some advantages, such as small sample volume and sensitivity. For example, by this method, it was investigated whether aspirin has an inhibitory effect on the release of platelet Factors. O 1995 Academic Press. Inc.