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Tertiary amines by palladium or nickel-catalyzed amination of ring-containing allylic systems

โœ Scribed by Gian Paolo Chiusoli; Mirco Costa; Luciano Pallini; Giuliana Terenghi


Publisher
Springer
Year
1981
Tongue
English
Weight
188 KB
Volume
6
Category
Article
ISSN
0340-4285

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Reaction of tertiary allylic amines with
โœ Christina Moberg ๐Ÿ“‚ Article ๐Ÿ“… 1981 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 183 KB

Tertiary allylic amines react with butadiene in the presence of palladium(O) with cleavage of the carbon-nitrogen bond of the allylic amine and formation of the unsaturated tertiarv amine 4. - In the course of our studies of nickel-catalyzed additions of secondary amines to butadiene,2 we found th

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Pd(PPh3)4-catalyzed cyclizations of N-allyl(croty1, or 3-butenyl),N-butenyloxy derivatives and of an allyl(2-butenyloxy) ether give pyrrolidines, piperidines and a tetrahydrofuran in good yields. Hexahydroindoles and octahydroquinolines are thus obtained from the corresponding N-(2-or 3-butenyl),N-(