✦ LIBER ✦
Tertiary amines: a decisive factor in the stereoselective addition of (R)-pantolactone to N-phthalyl valine ketene
✍ Scribed by Monique Calmes; Jacques Daunis; Nathalie Mai
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- French
- Weight
- 404 KB
- Volume
- 53
- Category
- Article
- ISSN
- 0040-4020
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✦ Synopsis
The stereoselective base-catalyzed addition of (R)-pantolactone to the ketene derived from racemic N-phthalyl valine is reported. The R or S configuration of the newly generated asymmetric centre of the pantolactonyl ester is highly dependent on the tertiary amine catalyst employed