Termal rearrangement of 1-alkyl-3,6-diaryl-1,4-dihydro-s-tetrazines to 1-alkylamino-3,5-diaryl-1,2,4-triazoles
β Scribed by Hunter, Daniel; Neilson, Douglas G.
- Book ID
- 121460511
- Publisher
- Royal Society of Chemistry
- Year
- 1984
- Weight
- 612 KB
- Category
- Article
- ISSN
- 1472-7781
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## Abstract Arylation of the readily available 3βalkythioβ5βarylβ1,2,4βtriazoles gave 5βalkylthioβ1,3βdiarylβ1,2,4βtriazoles in moderate yield. The structures of the latter were confirmed by NOE and ^13^CβNMR.
The reaction of 3,6-diaryl-1,2,4,5-tetrazines and 2-aryl substituted acetonitriles, under basic conditions, leads unexpectedly to 3,5-diaryl-(NH)-1,2,4-triazoles in moderate yields. A mechanism is proposed.