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Teriflunomide reduces behavioral, electrophysiological, and histopathological deficits in the Dark Agouti rat model of experimental autoimmune encephalomyelitis

✍ Scribed by Jean E. Merrill; Susan Hanak; Su-Fen Pu; Jinjun Liang; Chelsea Dang; Deborah Iglesias-Bregna; Brian Harvey; Bin Zhu; Kathleen McMonagle-Strucko

Publisher: Springer
Year: 2009
Tongue: English
Weight: 838 KB
Volume: 256
Category: Article
ISSN: 0340-5354
DOI: 10.1007/s00415-009-0075-3

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Ribavirin reduces clinical signs and pathological changes of experimental autoimmune encephalomyelitis in Dark Agouti rats

✍ Irena Milicevic; Sanja Pekovic; Sanja Subasic; Marija Mostarica-Stojkovic; Stani 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 500 KB

## Abstract The effect of ribavirin on development of experimental autoimmune encephalomyelitis (EAE) was investigated. The disease was induced in genetically susceptible Dark Agouti rats with syngeneic spinal cord homogenate in complete Freund's adjuvant (SCH‐CFA). Depending on the amount of mycob