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Teratogenicity of retinoic acid

โœ Scribed by Kochhar, Devendra M.

Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
37 KB
Volume
62
Category
Article
ISSN
0040-3709

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BACKGROUND: Epidermal growth factor (EGF) and transforming growth factor-โฃ (TGFโฃ) regulate cell proliferation and differentiation in the embryo. The induction of cleft palate (CP) by all trans-retinoic acid (RA) was associated with altered expression of TGFโฃ, EGF receptor, and binding of EGF. This s