Teratogenicity of anticonvulsant drugs. II: A prospective study
β Scribed by Kelly, Thaddeus E. ;Edwards, Pamela ;Rein, Marjorie ;Miller, James Q. ;Dreifuss, Fritz E.
- Publisher
- John Wiley and Sons
- Year
- 1984
- Tongue
- English
- Weight
- 578 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0148-7299
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## Abstract ## BACKGROUND Caseβcontrol studies have suggested that the nausea and vomiting of pregnancy (NVP) may have a protective effect against specific malformations. These suggestions have been interpreted as if the lack of NVP may put mothers at an increased teratogenic risk. ## METHODS A
As part of a prospective study of the teratogenicity of anticonvulsant drugs, hand radiographs were obtained on 51 children born to epileptic mothers. The phalanges and metacarpals were measured and a diagnosis of distal digital hypoplasia (DDH) was made if the distal phalangeal to other digital bon