Teratogenicity of 27.12-MHz radiation in rats is related to duration of hyperthermic exposure
✍ Scribed by Dr. Joseph M. Lary; David L. Conover; Peggy H. Johnson; Jénne R. Burg
- Publisher
- John Wiley and Sons
- Year
- 1983
- Tongue
- English
- Weight
- 462 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0197-8462
No coin nor oath required. For personal study only.
✦ Synopsis
Five groups of pregnant Sprague-Dawley rats were either sham exposed or were irradiated in a 27.12-MHz radiofrequency (RF) field at 55 A/m and 300 V/m on gestation day 9. The absorbed power (approximately I I W/kg) caused a relatively rapid increase in the rat's colonic temperature. Rats in group I were sham irradiated for 2.5 h at 0 A h . 0 V/m. In group I1 RF irradiation was terminated after the rat's colonic temperature reached 41 .O "C. In group Ill the 41.0-"C temperature was maintained an additional 2 h by manually varying the incident field strength. In group IV irradiation was terminated after the rat's colonic temperature reached 42.0 "C. In group V the 42.0-"C temperature was maintained an additional 15 min by varying the field strength. At both temperatures the teratogenic and embryotoxic effects of the RF-induced hyperthermia increased as the exposure duration increased, but the increase was especially noticeable at 42.0 "C. The results indicate that the teratogenic and embryotoxic effects of RF-induced hyperthermia are related to both the temperature of the dam during exposure and the length of time the dam's temperature remains elevated.