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Teratogenicity in vitro of 2-acetylaminofluorene: Role of biotransformation in the rat

โœ Scribed by Faustman-Watts, E. ;Greenaway, J. C. ;Namkung, M. J. ;Fantel, A. G. ;Juchau, M. R.


Book ID
112217249
Publisher
John Wiley and Sons
Year
1983
Tongue
English
Weight
816 KB
Volume
27
Category
Article
ISSN
0040-3709

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โœ Charlene A. McQueen; Mary Jo Miller; Gary M. Williams ๐Ÿ“‚ Article ๐Ÿ“… 1986 ๐Ÿ› Springer ๐ŸŒ English โš– 674 KB

Sex-related differences in susceptibility to 2-acetylaminofluorene (2-AAF) hepatocarcinogenicity and in vivo biotransformation of 2-AAF have been observed. In order to determine the contribution of hepatocytes to these differences, 2-AAF biotransformation was investigated in monolayer cultures of he