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Teratogenic effects of N-nitrosodiethylamine in embryos of the hermaphroditic fish Rivulus marmoratus

โœ Scribed by Eun-H. Park; Dr. Dong S. Kim; Hwa-H. Chang

Book ID
112213516
Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
341 KB
Volume
12
Category
Article
ISSN
0270-3211

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To investigate the patterns of alkylating agent-induced tumour formation, 40 fish (Rivulus marmoratus) were exposed to N-methyl-N-nitrosourea (MNU) at 50 ppm in 10 mM Hepes-buffered synthetic seawater for 2 h. Tumour incidence 4 months after exposure was approximately 95%, and mainly papillary thyro