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Teniposide (VM-26) and continuous infusion cytosine arabinoside for initial induction failure in childhood acute lymphoblastic leukemia. A pediatric oncology group pilot study

✍ Scribed by Judith Ochs; Gaston K. Rivera; Brad H. Pollock; George Buchanan; William Crist; Arnold I. Freeman

Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
595 KB
Volume
66
Category
Article
ISSN
0008-543X

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One hundred six children with newly diagnosed non-T-, non-B-cell acute lymphoblastic leukemia (ALL) were treated in a Pediatric Oncology Group (POG) pilot study in which six courses of intermediate-dose methotrexate (MTX) and cytosine arabinoside (Ara-C) (1 g/m2 each) were added to a "backbone" of s