Tendon and ligament engineering in the adult organism: mesenchymal stem cells and gene-therapeutic approaches

Intravenous administration of glial cell

Intravenous administration of glial cell line-derived neurotrophic factor gene-modified human mesenchymal stem cells protects against injury in a cerebral ischemia model in the adult rat

✍ Yoshifumi Horita; Osamu Honmou; Kuniaki Harada; Kiyohiro Houkin; Hirofumi Hamada 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 498 KB

## Abstract Intravenous administration of human mesenchymal stem cells (hMSCs) prepared from adult bone marrow has been reported to ameliorate functional deficits after cerebral artery occlusion in rats. Several hypotheses to account for these therapeutic effects have been suggested, and current th