Ten-year results of a randomized trial on adjuvant chemo-endocrine therapy with tamoxifen for stage II breast cancer
โ Scribed by Yoshinobu Hata; Hiromasa Takahashi; Satoru Todo; Minoru Okazaki; Kazuaki Asaishi; Koichi Hirata; Shunichi Okushiba; Hiroyuki Kato; Junichi Uchino
- Publisher
- Springer Japan
- Year
- 2003
- Tongue
- English
- Weight
- 478 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1340-6868
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## Abstract ## BACKGROUND This study evaluated the impact on overall survival (OS) of 2 versus 5 years adjuvant tamoxifen in early breast carcinoma patients after 12 years of followโup. ## METHODS Women with breast carcinoma T1โ3, N0โ3, M0, aged 50โ70 years, were eligible for this multicenter ra
Background. A randomized adjuvant trial was conducted from October 1982 to January 1985 to evaluate the addition of tamoxifen (TAM) to combination chemotherapy with perioperative mitomycin C (MMC) and ftorafur (FT) for patients with estrogen receptor (ER)-positive tumors and the addition of PSK, a b
## BACKGROUND. The use of adjuvant tamoxifen to treat postmenopausal breast carcinoma patients as an adjunct to primary surgery is well established. The current study reports the long term results for a low risk stratum in a randomized trial of adjuvant tamoxifen. The main focus of this analysis w