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Ten marker compounds-based comparative study of green tea and guava leaf by HPTLC densitometry methods: Antioxidant activity profiling

✍ Scribed by Imran Khan; Payare L. Sangwan; Sheikh Tasduq Abdullah; Bhisan D. Gupta; Jagdish K. Dhar; Rajendran Manickavasagar; Surrinder Koul


Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
482 KB
Volume
34
Category
Article
ISSN
1615-9306

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✦ Synopsis


Abstract

High‐performance thin layer chromatography (HPTLC) method for the separation and quantitative determination of ten markers (catechins, flavonoids, and phenolics) in different extracts of green tea and guava leaf has been developed and the antioxidant activity profiles of the two plant extracts have been determined. Ten marker compounds have been resolved using silica gel 60 F~254~ plates, toluene/acetone/formic acid (5:4:1 v/v/v) for markers 16, and toluene/ethyl acetate/formic acid/methanol (3:3:0.8:0.2 v/v/v/v) for markers 710 as the mobile phases. The high‐performance thin layer chromatography densitometry was performed at wavelengths of 282 and 285 nm for the markers 16 and 710, respectively. Potent antioxidant activity and the presence of phenolics and flavan‐3‐ols has been observed for the guava leaf extracts suggestive of its use as an alternate economical source of antioxidants over green tea – the well‐established food additive/nutraceutical agent.