✦ LIBER ✦

Temporary symptom worsening caused by manidipine hydrochloride in two patients with Parkinson's disease

✍ Scribed by K. Nakashima; M. Shimoda; N. Kuno; K. Takahashi

Publisher: John Wiley and Sons
Year: 1994
Tongue: English
Weight: 437 KB
Volume: 9
Category: Article
ISSN: 0885-3185
DOI: 10.1002/mds.870090119

No coin nor oath required. For personal study only.

✦ Synopsis

To the Editor:

The list of drugs that can induce parkinsonism has recently increased. Marti Mass6 et al. (1) emphasized the awareness of the possibility of inducing parkinsonism and the avoidance of certain drugs in patients with Parkinson's disease. Some patients with drug-induced parkinsonism caused by calcium antagonists have been reported (2-6). Manidipine hydrochloride, which has been developed and registered in Japan, is one of the new calcium channel blockers. We have experienced two cases of worsening parkinsonian symptoms after the use of manidipine, with improvements observed following the withdrawal of manidipine.

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