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Temporal requirements of insulin/IGF-1 signaling for proteotoxicity protection

✍ Scribed by Ehud Cohen; Deguo Du; Derek Joyce; Erik A. Kapernick; Yuli Volovik; Jeffery W. Kelly; Andrew Dillin


Book ID
111199604
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
633 KB
Volume
9
Category
Article
ISSN
1474-9718

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## Abstract Integrin receptors bind extracellular matrix proteins, and this link between the cell membrane and the surrounding matrix may translate skeletal loading to biologic activity in osteoprogenitor cells. The interaction between integrin and growth factor receptors allows for mechanically in