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Temporal profiles of aquaporin 4 expression and astrocyte response in the process of brain damage in fat embolism model in rats

✍ Scribed by Toru Gohara; Kazuyoshi Ishida; Kazuhiko Nakakimura; Mitsuyoshi Yoshida; Shiro Fukuda; Mishiya Matsumoto; Takefumi Sakabe


Publisher
Springer
Year
2010
Tongue
English
Weight
446 KB
Volume
24
Category
Article
ISSN
0913-8668

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## Abstract Aquaporin‐4 (AQP4), a water channel protein, is abundantly expressed in astrocytes and plays a key role in the development of brain edema. However, it is not clear whether AQP4 contributes to astrocytic swelling in hypoxia–ischemia (HI). To investigate the roles of AQP4 in astrocytic sw