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Temporal effects on antipyrine metabolite kinetics in aroclor 1254-treated rats

โœ Scribed by P.N. Shaw; J.B. Houston

Book ID
113206675
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
695 KB
Volume
84
Category
Article
ISSN
0041-008X

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๐Ÿ“œ SIMILAR VOLUMES

Antipyrine metabolite kinetics in rats:
Antipyrine metabolite kinetics in rats: Studies on dose and time dependence
โœ John C. Rhodes; J. Brian Houston ๐Ÿ“‚ Article ๐Ÿ“… 1983 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 512 KB

Antipyrine metabolite kinetics have been investigated in the rat with respect to dose and time dependence. The metabolic pathways, 4-hydroxylation, benzylic oxidation, and N-demethylation, are of equal quantitative importance (approximately 20 per cent of dose) and show no dose dependence over the r