Temporal distribution of human rotavirus serotypes 1, 2, 3, and 4 in venezuelan children with gastroenteritis during 1979–1989
✍ Scribed by Laura White; Dorys García; Yordi Boher; Mario Blanco; Mireya Pérez; Hans Romer; Jorge Flores; Irene Pérez-Schael
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 788 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0146-6615
No coin nor oath required. For personal study only.
✦ Synopsis
The temporal distribution and clinical severity of rotavirus VP7 serotypes 1, 2, 3, and 4 recovered from 427 Venezuelan children with acute gastroenteritis over a period of 11 years were studied. Rotavirus VP7 serotype was established by ELISA serotyping in 298 (69.78%) of the specimens while the serotype of the remaining 129 (30.21%) samples could not be determined. Of the specimens typed, 85 (19.90% of the total) were serotype 1, 43 (10.07%) were serotype 2, 105 (24.59%) were serotype 3, and 65 (15.22%) were serotype 4. Yearly changes in the frequency of individual serotypes were observed. The predominance of a single serotype with minor contribution from others was noted every year. In this study, serotype 1 appears to induce a less severe illness in comparison with serotypes 2, 3, and 4. No apparent association between the proportion of each serotype and the children's age were found.